方真，博士，副研究员，硕导
教育背景
2016.01至2016.07，美国伦斯勒理工大学生物技术和跨学科研究中心访问学者；
2011.09至2016.12，江南大学生物工程学院获博士学位；
2008.09至2011.09，江南大学生物工程学院获学士学位。
研究兴趣
应用酶分子的理性设计和表达（角蛋白酶等）；
合成生物学和代谢工程促进天然活性分子的高效合成；
荣誉/称号
1. 江苏省百篇优秀博士论文（2018）
2. 国家人社部/博管办“博新计划”获得者（2018，江苏大学第一位获奖者）
发表论文
1. Fang, Z., Jones, J. A., Zhou, J., & Koffas, M. A. (2018). Engineering Escherichia coli Co‐Cultures for Production of Curcuminoids From Glucose. Biotechnology journal, 13(5), 1700576.（杂志当月封面文章）
2. Zhang, C. L., Yu, Y. Y., Fang, Z., Naraginti, S., Zhang, Y., & Yong, Y. C. (2018). Recent advances in nitroaromatic pollutants bioreduction by electroactive bacteria. Process Biochemistry. 70, 129-135
3. Zhu, Z., Zhang, J., Ji, X., Fang, Z., Wu, Z., Chen, J., & Du, G. (2018). Evolutionary engineering of industrial microorganisms-strategies and applications. Applied microbiology and biotechnology, 102(11), 4615-4627.
4. Yu, Y. Y., Fang, Z., Gao, L., Song, H., Yang, L., Mao, B., ... & Yong, Y. C. (2018). Engineering of bacterial electrochemical activity with global regulator manipulation. Electrochemistry Communications, 86, 117-120.
5. Liu, X., Zhao, X., Yu, Y. Y., Wang, Y. Z., Shi, Y. T., Cheng, Q. W., Fang, Z., & Yong, Y. C. (2017). Facile fabrication of conductive polyaniline nanoflower modified electrode and its application for microbial energy harvesting. Electrochimica Acta, 255, 41-47.
6. Yang, Y., Wang, Y. Z., Fang, Z., Yu, Y. Y., & Yong, Y. C. (2018). Bioelectrochemical biosensor for water toxicity detection: generation of dual signals for electrochemical assay confirmation. Analytical and bioanalytical chemistry, 410(4), 1231-1236.
7. Yang, Y., Yu, Y. Y., Wang, Y. Z., Zhang, C. L., Wang, J. X., Fang, Z., ... & Yong, Y. C. (2017). Amplification of electrochemical signal by a whole-cell redox reactivation module for ultrasensitive detection of pyocyanin. Biosensors and Bioelectronics, 98, 338-344.
8. Fang, Z., Zhang, J., Du, G., & Chen, J. (2017). Rational protein engineering approaches to further improve the keratinolytic activity and thermostability of engineered keratinase KerSMD. Biochemical Engineering Journal, 127, 147-153.
9. Fang, Z., Yong, Y. C., Zhang, J., Du, G., & Chen, J. (2017). Keratinolytic protease: a green biocatalyst for leather industry. Applied microbiology and biotechnology, 101(21), 7771-7779.
10. Fang, Z., Zhang, J., Liu, B., Du, G., & Chen, J. (2016). Enhancement of the catalytic efficiency and thermostability of Stenotrophomonas sp. keratinase KerSMD by domain exchange with KerSMF. Microbial biotechnology, 9(1), 35-46.
11. Fang, Z., Zhang, J., Du, G., & Chen, J. (2016). Improved catalytic efficiency, thermophilicity, anti-salt and detergent tolerance of keratinase KerSMD by partially truncation of PPC domain. Scientific reports, 6.
12. Fang, Z., Zhang, J., Liu, B., Du, G., & Chen, J. (2015). Insight into the substrate specificity of keratinase KerSMD from Stenotrophomonas maltophilia by site-directed mutagenesis studies in the S1 pocket. RSC Advances, 5(91), 74953-74960.
13. Fang, Z., Zhang, J., Liu, B., Jiang, L., Du, G., & Chen, J. (2014). Cloning, heterologous expression and characterization of two keratinases from Stenotrophomonas maltophilia BBE11-1. Process Biochemistry, 49(4), 647-654.
14. Liu, B., Zhang, J., Fang, Z., Du, G., Chen, J., & Liao, X. (2014). Functional analysis of the C-terminal propeptide of keratinase from Bacillus licheniformis BBE11-1 and its effect on the production of keratinase in Bacillus subtilis. Process Biochemistry,49(9), 1538-1542.
15. Fang, Z., Zhang, J., Liu, B., Du, G., & Chen, J. (2013). Biodegradation of wool waste and keratinase production in scale-up fermenter with different strategies by Stenotrophomonas maltophilia BBE11-1. Bioresource technology,140, 286-291.
16. Fang, Z., Zhang, J., Liu, B., Du, G., & Chen, J. (2013). Biochemical characterization of three keratinolytic enzymes from Stenotrophomonas maltophilia BBE11-1 for biodegrading keratin wastes. International Biodeterioration & Biodegradation, 82, 166-172.
17.Liu, B., Zhang, J., Fang, Z., Gu, L., Liao, X., Du, G., & Chen, J. (2013). Enhanced thermostability of keratinase by computational design and empirical mutation. Journal of industrial microbiology & biotechnology, 40(7), 697-704.
